Active Pharmaceutical Ingredients (API)
API's are
typically produced by extraction or chemical syntheses. In most cases
afterwards the material is crystallised, mechanically separated and afterwards
dried. These steps can often be replaced by spray drying which not only allows
to control the humidity or residual solvent content but additionally also to
create materials with a tailor made particle size distribution and a dominant
amount of amorphous material.
Finished Drug Products
Finished drug
products are produced by mixing/blending API with excipients (polymers, fine
chemicals, etc.), solvents and others according to a specific formulation,
after which one or several process stages follow until the final dosage form is
reached.